Lymphology Association of North America (LANA) Practice Exam

Which of the following best describes the clinical signs of angiosarcoma?

1. Deep-purple, bruise-like lesions

2. Brownish discoloration with sclerosis

3. Reddish rash with fever and chills

4. Superficial redness with pain and chills

The correct answer is: Deep-purple, bruise-like lesions

Angiosarcoma is a rare and aggressive form of cancer that arises from the endothelial cells lining blood vessels. The clinical signs characteristic of angiosarcoma typically include lesions that appear as deep-purple, bruise-like spots on the skin. These lesions can be quite variable in appearance, but they often have a distinctive color due to the vascular nature of the tumor, which leads to bleeding and other changes in the skin. The deep-purple coloration is a result of the tumor's vascularity and the infiltration of blood into the surrounding tissues, leading to a bruise-like appearance. This can be an important visual cue for healthcare professionals when considering a diagnosis of angiosarcoma, as early recognition and diagnosis are crucial for effective treatment. Other options provided describe different conditions or states. For instance, brownish discoloration with sclerosis may suggest a chronic condition such as lymphedema or venous stasis but does not align with the acute and aggressive presentation of angiosarcoma. Reddish rash with fever and chills could be indicative of an infectious process or inflammation rather than a malignancy. Similarly, superficial redness with pain and chills could signal other inflammatory or infectious skin conditions. Overall, the unique presentation of deep-purple, bruise-like lesions