Lymphology Association of North America (LANA) Practice Exam

Malignant lymphedema is typically characterized by which of the following?

1. Slow onset, proximal edema, pain

2. Rapid onset, distal edema, pain

3. Rapid onset, proximal edema, pain

4. Slow onset, distal edema, no pain

The correct answer is: Rapid onset, proximal edema, pain

Malignant lymphedema is characterized by a rapid onset of symptoms, which can be indicative of an underlying malignancy affecting the lymphatic system. This rapid progression is often accompanied by proximal edema, meaning that the swelling typically occurs in areas closer to the trunk of the body rather than the extremities. The presence of pain is another key feature, as malignant processes often involve inflammation, tissue damage, or the growth of tumors that can affect local nerves. Understanding these characteristics is essential in distinguishing malignant lymphedema from other types of lymphedema, which may present differently, such as with slower onset or lack of pain. The emphasis on proximal edema further highlights how malignancies often impact lymphatic drainage from central areas of the body, whereas distal edema is more commonly seen in benign conditions. Thus, the combination of rapid onset, proximal edema, and pain provides a comprehensive picture that is critical for clinical assessment and timely intervention.