Lymphology Association of North America (LANA) Practice Exam

How does the lymphatic system respond to increased lymphatic load?

1. Increased low output failure

2. Increased lymph time volume (LTV)

3. Increased transport capacity (TC)

4. Increased colloid osmotic pressure

The correct answer is: Increased lymph time volume (LTV)

The lymphatic system responds to increased lymphatic load primarily by increasing lymph time volume (LTV). LTV refers to the volume of lymph that is moved through the lymphatic system over a specific time period. When there is an increase in lymphatic load—often due to factors like inflammation or injury—the lymphatic vessels undergo a series of adaptations to accommodate the extra fluid. This includes enhanced contractility of the lymphatic vessels, improved drainage through the lymphatic network, and possibly the development of new lymphatic channels. By increasing LTV, the lymphatic system can effectively manage excess interstitial fluid, maintain fluid homeostasis, and reduce the risk of lymphedema. This adaptive response is critical for the overall function of the lymphatic system, ensuring it can keep pace with varying physiological demands and prevent the accumulation of lymph. The other options do not accurately reflect the primary response of the lymphatic system to increased load. Low output failure pertains more to cardiovascular issues, while transport capacity (TC) involves the maximum volume of lymph that can be transported and does not specifically indicate an adaptive response to increased load. Increased colloid osmotic pressure relates to the balance of proteins in the blood and interstitial fluid rather than a direct response of the